Nabota
Experience medical-grade quality neurotoxin, specially designed by South Korean experts
Advanced botulinum toxin from Daewoong Pharmaceutical

- US FDA approved as Jeuveau
- 69+ countries with marketing authorization
- >98% 900 kDa complex purity
- 2 days to onset in glabellar lines
What is Nabota?

Nabota contains botulinum toxin type A, a neurotoxin that temporarily decreases nerve-to-muscle signaling at the treated site. By reducing targeted muscle activity, botulinum toxin can temporarily improve the appearance of certain dynamic facial lines, and can also be used for specific medical conditions where botulinum toxin treatment is indicated.
Sold internationally as Jeuveau, Nabota has a global visibility and an elevated reputation that many Korean neurotoxins lack. Daewoong describes Nabota as a botulinum toxin type A with high purity, emphasizing its purification technology and large-scale clinical validation, which result in a significantly lower risk of antibody formation with long-term use.
This international profile is one of Nabota’s strongest selling points for many practitioners and distributors, as it builds trust and patient reassurance.
The exact indications, patient populations, dosing, administration technique and regulatory status vary by country. Healthcare professionals should always consult the current Nabota prescribing information and applicable local requirements before use.
Nabota product range
Nabota is available in vial strengths from 50 to 200 units, so qualified healthcare professionals can select the appropriate presentation for their clinical practice. Strengths offered depend on market authorization and availability.
Nabota 50U
The 50-unit presentation provides a smaller vial option for clinical settings where a lower total amount of product is appropriate. Nabota 50U is a lyophilized botulinum toxin type A preparation supplied for reconstitution before professional administration, perfect for superficial facial wrinkles and treatment in sensitive areas.
Key details
- Botulinum toxin type A
- 50 units per vial
- Lyophilized powder for injection
- Professional medical use for fine facial wrinkles and sensitive areas
- Manufactured by Daewoong Pharmaceutical
Nabota 100U
Nabota 100U is one of the established presentations in Daewoong’s neurotoxin product line and is widely used as a professional botulinum toxin type A product. The 100-unit vial is supplied as a sterile lyophilized powder and must be reconstituted before administration. Its 100-unit strength makes it convenient and economical for medical professionals and patients alike, as it aligns with the standard, multi-area treatment of Botox procedures.
Key details
- Botulinum toxin type A
- The standard 100 units per vial, making it economically convenient
- Lyophilized powder for injection
- Prescription, professional medical product
- Manufacturer: Daewoong Pharmaceutical Co., Ltd.
Nabota 150U
Nabota 150U is designed as an intermediate presentation of the neurotoxin product line, for larger treatment areas but also economical enough for numerous treatment sessions. Nabota’s purity and potency maintain its durability even after reconstitution and proper storage, made possible by Daewoong’s innovative technology that tests Nabota’s efficacy and strength.
Key details
- Highly purified botulinum toxin type A
- 150 units per vial
- Lyophilized powder for injection
- Prescription, professional medical product for moderate to severe conditions
- Manufacturer: Daewoong Pharmaceutical Co., Ltd.
- Available in some regions
Nabota 200U
Nabota 200U provides a higher-strength vial presentation for professional clinical settings where the procedure requires a larger total amount of botulinum toxin due to severe conditions, such as deep facial wrinkles and depressions.
Key details
- Botulinum toxin type A
- 200 units per vial
- Lyophilized powder for injection, for great stability and potency
- Professional medical use for procedures needing larger amounts of the neurotoxin solution
- Manufacturer: Daewoong Pharmaceutical Co., Ltd., South Korea
Why choose Nabota?
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Korean pharmaceutical manufacturing
Nabota is developed and manufactured by Daewoong Pharmaceutical, a South Korean pharmaceutical company. Daewoong identifies Nabota as one of its biologic products and describes HI-PURE technology as part of its manufacturing platform.
DaewoongSouth Korean pharmaceutical company
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Pioneering purification technology
Nabota is manufactured using Daewoong’s proprietary HI-PURE technology, which is associated with the purification process used in the production of the botulinum toxin product. Nabota contains a high-purity toxin with more than 98% 900 kDa complex.
>98%900 kDa complex
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Multiple vial presentations
Nabota is offered in different strengths depending on market authorization and availability. Daewoong’s current official product listing identifies 50U, 100U and 200U presentations.
50–200UStrengths by market authorization
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Professional medical product
Nabota is a prescription, professional-use medicine in authorized markets. Treatment should be performed only by an appropriately qualified healthcare professional who is familiar with the administration of neuromuscular injectables.
RxPrescription, professional-use medicine
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Clinically proven efficacy and safety
Nabota’s efficacy and safety are recorded at a highly satisfactory rate in large-scale global clinical studies with more than 2,000 patients. Its toxin produces a rapid onset within 2 days, with proven effectiveness for various conditions and signs of aging, such as glabellar lines, blepharospasm, crow’s feet and muscle spasticity.
2,000+Patients in global clinical studies
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Highly regulated Asian botulinum toxin
Nabota, developed under the name DWP-450, is the first Asian botulinum toxin (900 kDa) to be approved by the US FDA, the EMA and Health Canada: as Jeuveau in the United States and as Nuceiva in Europe and Canada. It also has marketing authorizations in more than 69 countries worldwide, including in Europe and South America.
69+Countries with marketing authorizations
How does Nabota work?
- 1
Administered to the target area
Botulinum toxin type A works locally at nerve endings involved in muscle contraction. A professional administers it to the right target area.
- 2
Muscle activity is reduced
It temporarily reduces the release of acetylcholine, a neurotransmitter involved in muscle activation. This can soften the appearance of dynamic facial lines associated with repeated muscle movement.
- 3
The effect gradually wears off
The effect gradually wears off as normal neuromuscular communication returns.
A precise, targeted effect
To achieve natural results after treatment, the toxin must diffuse and work precisely. Nabota, having undergone numerous clinical trials, diffuses more precisely compared to other products, proving its targeted effect on the desired treatment area.
Rapid onset
Results and duration can vary depending on the treated area, individual patient characteristics, treatment technique, dose and other factors. However, Nabota demonstrated a rapid onset of action 2 days after administration for the treatment of glabellar lines. This confirms Nabota’s effectiveness, which influences each patient’s satisfaction with the results.
Nabota for aesthetic and therapeutic applications
Nabota is the first toxin with both upper and lower face indications.
Whole face
- Dynamic facial wrinkles Fine to severe dynamic facial wrinkles due to repetitive expressions
Upper face
- Glabellar lines Temporary improvement of moderate to severe glabellar lines (frown lines) US FDA and EMA approved
- Crow’s feet Reduction of crow’s feet or lateral canthal lines
- Blepharospasm Improvement in excessive blinking or eye twitching (blepharospasm)
Lower face
- Benign masseteric hypertrophy Also indicated for benign masseteric hypertrophy (enlarged jawline muscle) The world’s first botulinum toxin type A solution approved for this condition
Beyond the face
- Post-stroke upper limb spasticity Ideal for patients suffering from post-stroke upper limb spasticity
Approved indications vary by country.
Product quality and handling
Nabota is supplied as a lyophilized powder that requires reconstitution before administration. Proper storage and handling ensure the stability and effectiveness of the toxin solution.
Unopened Nabota should be refrigerated at 2–8 °C, and the reconstituted product may be refrigerated at 2–8 °C for up to 24 hours. Nabota should not be frozen.
- Unopened vials
- Refrigerate at 2–8 °C
- Reconstituted
- Up to 24 hours at 2–8 °C
- Freezing
- Do not freeze
Frequently asked questions
Have another question? Contact Nabota USA
Can Nabota be used therapeutically?
Nabota is a botulinum toxin type A product that temporarily reduces targeted muscle activity and is used for approved aesthetic and therapeutic indications. It is the first toxin with both upper and lower face indications, from the temporary improvement of glabellar lines and crow’s feet to blepharospasm, benign masseteric hypertrophy (enlarged jaw muscle) and post-stroke upper limb spasticity.
Who manufactures Nabota?
Nabota is manufactured by Daewoong Pharmaceutical Co., Ltd., Republic of Korea.
What strengths does Nabota come in?
Daewoong’s current official product listing identifies 50U, 100U and 200U Nabota presentations. In some regions, a 150-unit vial is also available.
How should Nabota be stored?
Unopened Nabota should be stored refrigerated at 2–8 °C, according to current product information. It should not be frozen. Reconstituted product should be handled according to the applicable prescribing information.
How does Nabota differ from other botulinum toxin products?
Nabota contains botulinum toxin type A; in the US, where it is approved as Jeuveau, the active ingredient is named prabotulinumtoxinA. Botulinum toxin products can differ in formulation, manufacturing, labeling, potency units and approved indications, so Nabota units should not be assumed to be directly interchangeable with units from other products.
Who can administer Nabota?
Nabota should be administered by an appropriately licensed and trained healthcare professional in accordance with local laws, approved indications and the current product information.
How long does Nabota last?
Clinical trials demonstrated that Nabota improves glabellar lines over 16 weeks, with progressive results to a more youthful appearance. However, the duration of effect varies between individuals and depends on the treatment area, dose, muscle activity, treatment technique and other factors. Patients should discuss expected duration with their treating healthcare professional.
Can Nabota be purchased for personal use?
Nabota is a prescription, professional medical product in regulated markets. It should be sourced and used through appropriate licensed channels and under professional medical supervision.
Explore Nabota
Learn more about Nabota presentations, product specifications, professional-use information and the manufacturer behind this Korean botulinum toxin product.




